Tetanus, Diphtheria, and Pertussis (Tdap/Td) Vaccines
Tetanus, Diphtheria, and Pertussis (Whooping Cough) are serious bacterial infections that can cause life-threatening complications.
While most people receive these vaccines in childhood, protection decreases over time—making periodic booster doses essential for adults, especially in workplace and healthcare settings.
Affinity Vaccines provides TDaP and TD vaccines approved by the Philippine FDA and World Health Organization (WHO) for both adult booster and occupational immunization programs.
A. Boostrix® (GlaxoSmithKline – GSK)
Formulation:
Acellular combination vaccine containing:
- Diphtheria toxoid (≥ 2 IU)
- Tetanus toxoid (≥ 20 IU)
- Acellular pertussis antigens (pertussis toxoid, filamentous hemagglutinin, pertactin)
Packaging:
Single-dose pre-filled syringe, 0.5 mL per dose.
Dosage and Administration:
- Adults and adolescents (≥ 10 years): Single 0.5 mL intramuscular injection, usually in the deltoid.
- May be given as a booster every 10 years, or sooner in case of contaminated wound injury.
- Can be administered during pregnancy (preferably 27–36 weeks gestation) to protect newborns from pertussis.
Indications:
Active booster immunization against tetanus, diphtheria, and pertussis in adolescents and adults.
Contraindications:
- Hypersensitivity to any component or previous dose of Tdap/Td vaccine.
- History of encephalopathy within 7 days after previous pertussis vaccine dose.
- Defer during moderate or severe febrile illness.
Storage / Cold-Chain Requirement:
- Store between +2°C and +8°C.
- Do not freeze.
- Protect from light.
Manufacturer:
GlaxoSmithKline Biologicals S.A., Belgium
B. Adacel® (Sanofi Pasteur)
Formulation:
Acellular Tdap vaccine containing tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis antigens.
Packaging:
Single-dose pre-filled syringe, 0.5 mL per dose.
Dosage and Administration:
- Adults and adolescents (≥ 10 years): One 0.5 mL intramuscular injection in the deltoid.
- Booster interval: Every 10 years, or sooner for wound management.
- May be administered during pregnancy.
Indications:
Active booster immunization against tetanus, diphtheria, and pertussis in individuals 10 years and older.
Contraindications:
- Hypersensitivity to any vaccine component or prior TDaP/TD dose.
- Postpone during acute moderate or severe illness.
Storage / Cold-Chain Requirement:
- Maintain +2°C to +8°C.
- Do not freeze.
- Protect from light.
Manufacturer:
Sanofi Pasteur S.A., France
C. Td-Vax® (Sanofi Pasteur)
Formulation:
Adsorbed Tetanus and Diphtheria toxoids (reduced content) for adult and adolescent use.
Packaging:
Single-dose pre-filled syringe, 0.5 mL per dose.
Dosage and Administration:
- Adults and adolescents (≥ 7 years): 0.5 mL intramuscular injection.
- Routine booster every 10 years, or earlier after contaminated wounds.
- May be used in rotation with TDaP boosters (e.g., one TDaP, followed by Td every 10 years).
Indications:
Active immunization against tetanus and diphtheria in adults and children 7 years and older.
Contraindications:
- Hypersensitivity to any component or prior Td/TDaP vaccine.
- Defer during acute febrile illness.
Storage / Cold-Chain Requirement:
- Store between +2°C and +8°C.
- Do not freeze.
- Protect from light.
Manufacturer:
Sanofi Pasteur S.A., France
Corporate Vaccination Recommendations (Upon Availability)
Target Group | Recommended Vaccine | Notes |
All adults (every 10 years) | Boostrix® / Adacel® / Td-Vax® | Maintain immunity against tetanus and diphtheria. |
Healthcare, construction, and service workers | Boostrix® / Adacel® (TDaP) | Prevents pertussis spread and wound-related infections. |
Pregnant employees (27–36 weeks) | Boostrix® / Adacel® | Provides passive immunity to newborns. |
Post-injury or contaminated wound | Td-Vax® or TDaP booster | Immediate protection as part of wound care protocol. |
Affinity Vaccines Recommendation:
Use TDaP (Boostrix® or Adacel®) for adult boosters whenever possible to include pertussis protection. Alternate with Td-Vax® every 10 years for continued tetanus and diphtheria coverage.
Cold-Chain and Safety Assurance
All Tdap/Td vaccines are stored and transported within +2 °C to +8 °C and never frozen.
Affinity Vaccines ensures full cold-chain integrity, licensed administration, and post-vaccination observation for every employee immunization program.
Protect Your People. Protect Your Business. Strengthen Your Organization.
Tetanus, diphtheria, and pertussis can strike unexpectedly—but prevention is simple and long-lasting.
Affinity Vaccines provides corporate TDaP/Td vaccination programs for employees and dependents, protecting against life-threatening infections while meeting occupational health standards.
📩 Request for a Corporate Vaccination Proposal
Email: vaccines@affinity.com.ph