Hepatitis Vaccines

Hepatitis A and B are preventable viral infections that can lead to serious liver disease, long-term complications, and costly absences in the workplace.

Affinity Vaccines supplies and administers monovalent and combination Hepatitis vaccines approved by the Philippine FDA and the World Health Organization (WHO)—suitable for adult, pediatric, and corporate immunization programs.

All vaccines are handled with strict cold-chain compliance and administered by licensed medical professionals under DOH guidelines.

A. Hepatitis A Vaccines

1. Avaxim® 160 U Adult / Avaxim® 80 U Pediatric (Sanofi Pasteur)

Formulation:

Inactivated Hepatitis A virus (strain GBM) adsorbed on aluminum hydroxide.

Packaging:

0.5 mL pre-filled syringe (single dose).

Dosage and Administration:

Adults ≥ 16 years: 0.5 mL IM in deltoid; booster 6–12 months after first dose.
Children 12 months–15 years: 0.5 mL IM; booster 6–18 months later.

Indications:

Active immunization against infection caused by Hepatitis A virus.

Contraindications:

Hypersensitivity to any component (e.g., neomycin, formaldehyde).
Defer vaccination during acute or severe illness.

Storage / Cold Chain Requirement:

Store at +2°C to +8°C.
Do not freeze. Protect from light.

Manufacturer:

Sanofi Pasteur S.A., France

2. Havrix® 720 / 1440 (GlaxoSmithKline – GSK)

Formulation:

Inactivated Hepatitis A virus (strain HM175) adsorbed on aluminum hydroxide.

Packaging:

0.5 mL (720 ELISA Units, pediatric) / 1.0 mL (1440 ELISA Units, adult) pre-filled syringe.

Dosage and Administration:

Adults ≥ 19 years: 1 mL IM; booster after 6–12 months.
Children 1–18 years: 0.5 mL IM; booster after 6–12 months.

Indications:

Active immunization against Hepatitis A infection.

Contraindications:

Hypersensitivity to vaccine components (including neomycin).
Postpone vaccination if febrile or acutely ill.

Storage / Cold Chain Requirement:

Keep at +2°C to +8°C.
Do not freeze.

Manufacturer:

GlaxoSmithKline Biologicals S.A., Belgium

B. Hepatitis B Vaccines

1. Engerix-B® (GSK)

Formulation:

Recombinant Hepatitis B surface antigen (HBsAg) expressed in yeast, adsorbed on aluminum hydroxide.

Packaging:

Single-dose pre-filled syringe: 0.5 mL (10 µg, pediatric) or 1.0 mL (20 µg, adult).

Dosage and Administration:

Adults ≥ 19 years: 3 doses (0, 1, and 6 months).
Children and infants: 3 doses (0, 1, and 6 months) or per national immunization schedule.

Indications:

Active immunization against all known subtypes of Hepatitis B virus.

Contraindications:

Hypersensitivity to yeast or any component.
Defer vaccination in case of acute febrile illness.

Storage / Cold Chain Requirement:

+2°C to +8°C. Do not freeze.

Manufacturer:

GlaxoSmithKline Biologicals S.A., Belgium

C. Combined Hepatitis A + B Vaccine

1. Twinrix® (GSK)

Formulation:

Inactivated Hepatitis A virus (720 ELISA Units) combined with recombinant Hepatitis B surface antigen (20 µg).

Packaging:

Pre-filled syringe, 1.0 mL (single adult dose).

Dosage and Administration:

Adults ≥ 19 years: 3 doses (0, 1, and 6 months).
Accelerated schedule: 0, 7, and 21 days + booster at 12 months (optional for travelers).

Indications:

Active immunization against both Hepatitis A and B viruses in adults and adolescents.

Contraindications:

Hypersensitivity to any component or prior Hepatitis A/B vaccination.
Postpone if febrile or acutely ill.

Storage / Cold Chain Requirement:

+2°C to +8°C. Do not freeze.

Manufacturer:

GlaxoSmithKline Biologicals S.A., Belgium

Corporate Vaccination Recommendations

Target Group	Recommended Vaccine	Notes
Food industry, healthcare, or hospitality workers	Twinrix® (A+B)	Dual protection from occupational exposure.
Adults with no Hepatitis B immunity	Engerix-B®	Standard 3-dose series.
Travelers to high-risk areas	Avaxim® / Havrix® / Twinrix®	Add booster as needed.
Children and dependents	Avaxim® / Havrix® + Engerix-B®	Safe and pediatric-approved.

Affinity Vaccines Recommendation:

For adult workplace programs, Twinrix® offers the most efficient dual protection against Hepatitis A and B in a single 3-dose series.

Cold-Chain and Quality Assurance

All Hepatitis vaccines are transported and administered under strict temperature monitoring (2 °C – 8 °C) and handled only by licensed healthcare professionals.

Vaccination records and post-administration monitoring are standard in every corporate program.

Protect Your People. Protect Your Business. Strengthen Your Organization.

Hepatitis infections are preventable through safe and reliable vaccination.

Affinity Vaccines provides Hepatitis A, B, and combination (A+B) vaccines through fully managed corporate immunization programs for employees and dependents.

📩 Request for a Corporate Vaccination Proposal

Email: vaccines@affinity.com.ph